Popularly known as the body's natural tranquilizer, gamma aminobutyric acid (GABA) is the major inhibitory neurotransmitter of the nervous system. It is an important factor in reducing pain levels and hypersensitivities in the peripheral nervous system. New research shows GABA can cross the blood-brain-barrier, contributing to normal mood. Poor diet, oxidative stress and other factors can deplete normal levels of GABA and may result in anxiety, irritability and insomnia. Open capsule and mix in water for optimal results.